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Medical ultrasonic scanner is a kind of equipment that uses ultrasound for non-invasive detection, which is widely used in the medical field. In recent years, with the continuous development of technology, medical ultrasonic scanner has also played an important role in drug delivery and gene therapy. This article will discuss the application and principle of medical ultrasonic scanner in drug delivery and gene therapy, and elaborate its advantages and prospects.
1、 Introduction of medical ultrasonic scanner
Medical ultrasonic scanner can obtain the structure and lesion information of human body by using the penetration and reflection of ultrasound. Compared with traditional imaging examination, medical ultrasonic scanning has the advantages of noninvasive, non radiation, simple operation and so on. It is widely used in the process of diagnosis, treatment and follow-up.
2、 Application in drug delivery
Drug directed delivery
Using the acoustic characteristics of medical ultrasonic scanner, drugs can be targeted to the lesion. By combining drugs with ultrasound, a drug ultrasound complex is formed, which can act on the diseased tissue, improve the curative effect of drugs and reduce side effects.
Drug penetration enhancement
The ultrasonic vibration of medical ultrasonic scanner can produce microfluidic effect, enhance the permeability of cell membrane, and promote the penetration of drugs into cells. This effect can improve the bioavailability of drugs and enhance the efficacy of drugs.
Real time monitoring of drug distribution
Through the medical ultrasonic scanner, the distribution of drugs in the body can be monitored in real time. This helps to understand the metabolic process and distribution characteristics of drugs, and provides a basis for the optimal design and rational use of drugs.
3、 Application in gene therapy
Gene vector preparation
Gene therapy is a method of using gene vectors to introduce target genes into human cells to treat some genetic diseases. Medical ultrasonic scanners can be used to prepare gene carriers, such as liposomes, nanoparticles, etc. These vectors can protect genes from the in vivo environment and improve the stability of genes.
Gene introduction
Using the acoustic characteristics of medical ultrasonic scanner, gene vectors can be efficiently introduced into target cells. This introduction method has the advantages of high efficiency, safety and non-invasive, and provides a new way for gene therapy.
Gene expression regulation
Medical ultrasonic scanner can regulate gene expression by adjusting the parameters of ultrasound. Through specific ultrasonic stimulation, the expression of target genes can be induced, so as to achieve the purpose of treating diseases.
4、 Advantages and Prospects
advantage
Medical ultrasound scanners have the following advantages in drug delivery and gene therapy: first, ultrasound has the advantages of strong penetration, good directionality, energy concentration and so on, which can effectively deliver drugs or genes to the lesion site; Secondly, the medical ultrasonic scanner is easy to operate, safe and reliable, and suitable for wide clinical application; Finally, by combining with other technologies, such as MRI and CT, the real-time monitoring of drug distribution and gene expression can be realized to improve the therapeutic effect.
prospect
With the continuous development of technology, medical ultrasonic scanners have broad application prospects in drug delivery and gene therapy. In the future, we can explore more potential of ultrasound through further research and practice. For example, the delivery and distribution of drugs and genes can be better regulated by optimizing the parameters and waveform of ultrasound; At the same time, combining with more biomedical engineering technologies, such as nanotechnology and biomaterial technology, can further improve the effect of drug delivery and gene therapy. In addition, with the development of artificial intelligence, big data and other technologies, medical ultrasonic scanners are expected to achieve more accurate and personalized treatment strategies.
conclusion
Medical ultrasonic scanner plays an important role in drug delivery and gene therapy. Through the combination with drugs and genes, the directional delivery of drugs, penetration enhancement, and the preparation and introduction of gene carriers can be achieved. At the same time, using the advantages of medical ultrasonic scanner, the distribution of drugs and genes in the body can be monitored in real time to improve the therapeutic effect. With the continuous development of technology, medical ultrasonic scanners have broad application prospects in drug delivery and gene therapy
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